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Promethazine Promethazine is an antihistamine that is used for allergy relief, mild sedation, and prevention and control of nausea. Promethazine is an antihistamine that can be taken by mouth, as a tablet or syrup, rectally as a suppository, or by injection. It is used for hay fever; stuffy nose from allergy; watery, itchy eyes due to inhaled allergies; and for mild allergic skin reactions.
The potential risks and side effects include severe drowsiness and
reduced mental alertness. It may impair a patient's ability to ride
a bike, drive a car, or operate machinery. This may be worsened if
taken with alcohol or other drugs that also cause central nervous
system slowing such as sedatives, pain medicines, tranquilizers, or
certain drugs for depression. Promethazine should be used with
caution in patients with seizures or who are on other medicines, which
may also increase the risk of seizures. Promethazine should not be
used in patients with bone-marrow problems or used with other drugs
that affect the bone marrow's production of blood cells.
The most common side effects are drowsiness, changes in blood pressure, skin
reactions, blood cell changes, and breathing problems. Increased
excitability or abnormal movements may occur after one dose of
promethazine. If they do, patients should consult a doctor about using another medicine.
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